Novel phospholipid vesicular carrier formulation for several cosmetic applications

Supervisor Name

Hiba Natsheh

Supervisor Email

hiba.natsheh@najah.edu

University

An-Najah National University

Research field

Pharmaceutical Sciences

Bio

Dr. Hiba Natsheh is an Assistant Professor at the Faculty of Pharmacy, An-Najah National University. She also serves as the Head of the Pharmaceutical Research Unit and a member of the Pharmaceutical Nanotechnology Research Group at The Medical and Health Sciences Research Center, Scientific Centers, An-Najah National University. In her research, Dr. Natsheh focuses on multidisciplinary research aiming to develop novel delivery systems for medical and cosmetic applications. She co-authored several publications including original research and review articles and a book chapter. In addition, she is a co-inventor of seven patents and patent applications and a recipient of the prestigious Kaye innovation award, The Hebrew University of Jerusalem, 2022 for her contribution to the invention of a new nanotechnology to enhance drug delivery to the brain.

Description

This project focuses on developing a novel phospholipid nanovesicle cosmetic formulation designed to enhance the delivery of bioactive compounds into the skin. The system is based on engineered phospholipid nanovesicles that mimic the structural properties of natural exosomes, allowing improved penetration, stability, and controlled release of active ingredients. The formulation is incorporated into a topical gel matrix intended for multiple cosmetic applications, including skin rejuvenation, collagen stimulation, barrier repair, pigmentation improvement, and wound healing. The novelty of this approach lies in creating a synthetic exosome-mimetic nanovesicle delivery system integrated into a topical cosmetic formulation, offering a more stable, scalable, and cost-effective alternative to natural exosomes while maintaining their potential regenerative and skin-communication benefits.